Enzymes of N-Acetylglucosamine Metabolism during Germ-tube Formation in Candida albicans
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چکیده
منابع مشابه
Hemin induces germ tube formation in Candida albicans.
Hemin induced germination of Candida albicans blastoconidia when cells grown up to the early exponential phase were shifted from 28 to 37 degrees C (70 to 75% of cells exhibited germ tubes). N-Acetyl-D-glucosamine (GlcNAc), another inducer of myceliation in this fungus, caused a similar effect. The combination of hemin and GlcNAc resulted in a higher percentage (95%) of blastoconidial germinati...
متن کاملProline-induced germ-tube formation in Candida albicans: role of proline uptake and nitrogen metabolism.
Proline-induced germ-tube formation and cell-cell aggregation in four strains of Candida albicans were completely inhibited when the pH of the medium was 5.0 or lower, whereas morphogenesis induced by N-acetylglucosamine (GlcNAc) was unaffected even at pH 4.5. The pH sensitivity of proline-induced germ-tube formation was not caused by a modulation of proline uptake, which was unchanged over the...
متن کاملN-Acetylglucosamine Metabolism Promotes Survival of Candida albicans in the Phagosome
Phagocytosis by innate immune cells is one of the most effective barriers against the multiplication and dissemination of microbes within the mammalian host. Candida albicans, a pathogenic yeast, has robust mechanisms that allow survival upon macrophage phagocytosis. C. albicans survives in part because it can utilize the alternative carbon sources available in the phagosome, including carboxyl...
متن کاملIdentification of the dialysable serum inducer of germ-tube formation in Candida albicans.
Yeast cells of Candida albicans are induced by serum at 37 degrees C to produce germ tubes, the first step in a transition from yeast to hyphal growth. Previously, it has been shown that the active component is not serum albumin but is present in the dialysable fraction of serum. In this study, serum induction of germ-tube formation is shown to occur even in the presence of added exogenous nitr...
متن کاملIn Vitro Effect of Local Anesthetics on Candida albicans Germ Tube Formation
OBJECTIVE This study was planned to clarify the in vitro effect of lidocaine and bupivacaine on germ tube formation by Candida albicans isolates from cases of clinical vaginal candidiasis. METHODS Fourteen C. albicans strains (clinical vaginal isolates) were grown on Sabouraud agar for 24 h at 37 and tested as follows: 100 microl of a yeast suspension [10(5) colony forming units (CFU)/ml of p...
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ژورنال
عنوان ژورنال: Microbiology
سال: 1982
ISSN: 1350-0872,1465-2080
DOI: 10.1099/00221287-128-10-2319